The 414’s high sampling rate (40 kHz) allows detection of 5mC and 6mA via residual current deviations, with sensitivity of 92% and specificity 94% compared to bisulfite sequencing.
The portability of the 414 unit is not a gimmick; it is solving problems that benchtop sequencers cannot touch. portable sequencher 414
The "414" often references the latest generation of nanopore flow cell, the R10.4.1. This chip contains 2,672 active nanopores configured in 414 distinct channels (hence the numeric homage). These channels provide: The 414’s high sampling rate (40 kHz) allows