The cheats developed for MHGU fall into distinct categories, each affecting the gameplay loop differently.
Unlike Citra or Ryujinx, Yuzu has a specific file structure for cheats. Follow these steps carefully.
Navigate to:
yuzu\load\0100770008DD8000\cheats\ (Create the cheats folder if it doesn't exist).
Yuzu does not officially support online play for MHGU via Nintendo servers (due to lack of real console keys). But if you use Lan-Play or Parsec to play with friends, do not use active cheats like infinite health. The host's game may desync, crashing everyone's session.