1. Create your tweak file (apply-tweaks.reg)
Windows Registry Editor Version 5.00; Disable ULPS for all AMD GPUs [HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Class4d36e968-e325-11ce-bfc1-08002be10318\0000] "EnableUlps"=dword:00000000
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Class4d36e968-e325-11ce-bfc1-08002be10318\0001] "EnableUlps"=dword:00000000
2. Create a revert file (revert-tweaks.reg)
Windows Registry Editor Version 5.00; Re-enable ULPS [HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Class4d36e968-e325-11ce-bfc1-08002be10318\0000] "EnableUlps"=dword:00000001 "EnableUlps_NA"=dword:00000001
; Same for 0001 if needed
3. Apply portably
Run apply-tweaks.reg → reboot for full effect.
Run revert-tweaks.reg → reboot to undo.
Limitation: Requires reboot, not fully “live portable.” amd registry tweaks portable
These tweaks modify how the CPU and GPU handle instruction processing.
The true power of registry tweaks for portable users is the ability to apply them quickly via a .bat or .reg file. You can keep this script on your USB drive to apply your preferred settings on any PC with an AMD card instantly.
Force the GPU to handle command buffers with higher priority than default. Limitation: Requires reboot